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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
shares in Millions, $ in Millions
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Revenue:      
Total revenue $ 6,848 $ 19,263 $ 18,471 Close
Operating expenses:      
Cost of sales 4,693 5,416 2,617
Research and development 4,845 3,295 1,991
Selling, general and administrative 1,549 1,132 567
Total operating expenses 11,087 9,843 5,175 Close
(Loss) income from operations (4,239) 9,420 13,296 Close
Interest income 421 200 18 Close
Other expense, net (124) (45) (29) CloseClose
Total Other Income Expenses 297.0 155.0 -11.0 0.0 0 Close
(Loss) income before income taxes (3,942) 9,575 13,285 CloseClose
Provision for income taxes 772 1,213 1,083 Close
Net (loss) income $ (4,714) $ 8,362 $ 12,202 Close
(Loss) earnings per share:      
Basic (in usd per share) $ (12.33) $ 21.26 $ 30.31
Diluted (in usd per share) $ (12.33) $ 20.12 $ 28.29
Weighted average common shares used in calculation of (loss) earnings per share:      
Basic (in shares) 382 394 403
Diluted (in shares) 382 416 431
Net product sales      
Revenue:      
Total revenue $ 6,671 $ 18,435 $ 17,675
Other revenue      
Revenue:      
Total revenue $ 177 $ 828 $ 796