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Consolidated Statements of Operations - USD ($)
shares in Thousands, $ in Millions
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Income Statement [Abstract]      
Revenue (Note 2) $ 34,124.1 $ 28,541.4 $ 28,318.4 Close
Costs, expenses, and other:      
Cost of sales 7,082.2 6,629.8 7,312.8
Research and development 9,313.4 7,190.8 6,930.7
Marketing, selling, and administrative 7,403.1 6,440.4 6,431.6
Acquired in-process research and development (Note 3) 3,799.8 908.5 970.1
Asset impairment, restructuring, and other special charges (Note 5) 67.7 244.6 316.1
Other—net, (income) expense (Note 18) (96.7) 320.9 201.6
Costs, expenses, and other 27,569.5 21,735.0 22,162.9
Income before income taxes 6,554.6 6,806.4 6,155.5 Close
Income taxes (Note 14) 1,314.2 561.6 573.8 Close
Net income $ 5,240.4 $ 6,244.8 $ 5,581.7 Close
Earnings per share:      
Basic (in dollars per share) $ 5.82 $ 6.93 $ 6.15
Diluted (in dollars per share) $ 5.80 $ 6.90 $ 6.12
Shares used in calculation of earnings per share:      
Basic (in shares) 900,181 901,736 906,963
Diluted (in shares) 903,284 904,619 911,681