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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Millions
9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Cash flow from operating activities:    
Net income $ 912.6 $ 2,412.1
Adjustments to reconcile net income to net cash flow from operating activities:    
Depreciation and amortization 354.7 398.6
Excess and obsolescence charges related to inventory 62.1 321.6
Share-based compensation 209.3 186.9
Contingent consideration 0.0 (13.7)
Deferred income taxes (377.7) (139.8)
(Gain) loss on strategic investments 275.7 160.3
(Gain) loss on equity method investments 0.0 (2.6)
Gain on sale of equity interest in Samsung Bioepis 0.0 (1,505.4)
Gain on sale of building 0.0 (503.7)
Other 98.6 147.8
Changes in operating assets and liabilities, net:    
Inventory (34.9) (338.3)
Accrued expense and other current liabilities 293.9 632.3
Income tax assets and liabilities (114.8) (100.2)
Other changes in operating assets and liabilities, net (71.4) 15.9
Net cash flow provided by (used in) operating activities 1,534.7 1,559.3 Close
Cash flows from investing activities:    
Purchases of property, plant and equipment (211.8) (153.9)
Proceeds from sales and maturities of marketable securities 7,380.8 3,104.7
Purchases of marketable securities (5,140.7) (2,805.9)
Acquisition of Reata, net of cash acquired (6,335.6) 0.0
Proceeds from sale of equity interest in Samsung Bioepis 788.1 990.3
Acquisitions of intangible assets (34.4) (1.9)
Proceeds from sales of strategic investments 106.2 0.0
Other (1.3) 1.8
Net cash flow provided by (used in) investing activities (3,448.7) 1,717.7 Close
Cash flows from financing activities:    
Purchases of treasury stock 0.0 750.0
Payments related to issuance of stock for share-based compensation arrangements, net (48.0) (5.8)
Repayment of borrowings and premiums paid 159.9 1,002.2
Proceeds from borrowings, net 997.2 0.0
Net (distribution) contribution to noncontrolling interest 4.2 12.2
Other 1.9 5.9
Net cash flow provided by (used in) financing activities 795.4 (1,739.9) Close
Net increase (decrease) in cash and cash equivalents (1,118.6) 1,537.1 Close
Effect of exchange rate changes on cash and cash equivalents (12.8) (122.9)
Cash and cash equivalents, beginning of the period 3,419.3 2,261.4
Cash and cash equivalents, end of the period 2,287.9 3,675.6
Nonrelated Party    
Changes in operating assets and liabilities, net:    
Accounts receivable (76.5) (109.5)
Related Party    
Changes in operating assets and liabilities, net:    
Accounts receivable $ 3.1 $ (3.0)