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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Millions
6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Cash flow from operating activities:    
Net income $ 980.9 $ 1,277.2
Adjustments to reconcile net income to net cash flow from operating activities:    
Depreciation and amortization 229.7 277.9
Excess and obsolescence charges related to inventory 36.8 305.6
Share-based compensation 147.1 123.3
Contingent consideration 0.0 (11.6)
Deferred income taxes (170.9) (47.5)
(Gain) loss on strategic investments (26.8) 269.3
(Gain) loss on equity method investments 0.0 (2.6)
Gain on sale of equity interest in Samsung Bioepis 0.0 (1,505.4)
Other 60.5 112.2
Changes in operating assets and liabilities, net:    
Inventory (65.1) (243.3)
Accrued expense and other current liabilities (127.1) 634.0
Income tax assets and liabilities (82.4) (65.9)
Other changes in operating assets and liabilities, net (55.5) (134.0)
Net cash flow provided by (used in) operating activities 942.3 898.3 Close
Cash flows from investing activities:    
Purchases of property, plant and equipment (137.6) (94.8)
Proceeds from sales and maturities of marketable securities 1,682.2 1,461.5
Purchases of marketable securities (4,120.3) (2,311.6)
Proceeds from sale of equity interest in Samsung Bioepis 788.1 990.3
Acquisitions of intangible assets (21.0) (1.9)
Proceeds from sales of strategic investments 103.2 0.0
Other (1.1) 2.0
Net cash flow provided by (used in) investing activities (1,706.5) 45.5 Close
Cash flows from financing activities:    
Purchases of treasury stock 0.0 500.0
Payments related to issuance of stock for share-based compensation arrangements, net (54.6) (11.5)
Net (distribution) contribution to noncontrolling interest 1.7 12.1
Other (0.3) 11.4
Net cash flow provided by (used in) financing activities (53.2) (488.0) Close
Net increase (decrease) in cash and cash equivalents (817.4) 455.8 Close
Effect of exchange rate changes on cash and cash equivalents 15.9 (70.6)
Cash and cash equivalents, beginning of the period 3,419.3 2,261.4
Cash and cash equivalents, end of the period 2,617.8 2,646.6
Nonrelated Party    
Changes in operating assets and liabilities, net:    
Accounts receivable 21.8 (67.3)
Related Party    
Changes in operating assets and liabilities, net:    
Accounts receivable $ (6.7) $ (23.6)