Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We consent to the incorporation by reference, in the Prospectus constituting a part of this Registration Statement on Form S-1, of our report dated March 25, 2021 relating to the consolidated financial statements of NovaBay Pharmaceuticals, Inc., which appears in its Annual Report on Form 10-K for the year ended December 31, 2020.

We also consent to the reference to us under the caption “Experts” in the Prospectus.

/s/ OUM & CO. LLP

San Francisco, California

December 1, 2021